产品货号：
Z27757
中文名称：
Tamalin/GRASP抗体
英文名称：
Anti-Tamalin/GRASP Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Tamalin/GRASP Antibody |
| 指标别名 | Tamalin,Grasp,GRASP 1,GRP1-associated scaffold protein,GRIP associated protein 1,GRIP1 associated protein 1,GRIPAP 1,General receptor for phosphoinositides 1-associated scaffold protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | GRASP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the amino terminus of mouse Tamalin protein. |
| 计算分子量 | 43kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity purified antibody is directed against mouse Tamalin protein.The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.?A BLAST analysis was used to suggest cross-reactivity with Tamalin protein from rat based on a 94% homology with the immunizing sequence.Reactivity against homologues from other sources is not known. |
| 浓度 | 1.03mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.Tamalin,also named General receptor for phosphoinositides 1-associated scaffold protein (GRASP) is a PDZ (post-synaptic density protein/Drosophila disc large tumor suppressor/zo-1) domain-containing protein that interacts with group 1 metabotropic glutamate receptors (mGluRs).?The PDZ domain-containing amino-terminal half of Tamalin binds directly to the class I PDZ-binding motif of group 1 mGluRs.?The carboxyl-terminal half of Tamalin binds to cytohesins,which are guanine nucleotide exchange factors (GEFs) specific for the ADP-ribosylation factor (ARF) family of small GTP-binding proteins.Tamalin forms a protein complex with group 1 mGluRs at the post-synaptic site of specific neuronal cells and serves as a key scaffold protein that links a complex formation between mGluR1a and cytohesins.?It is reported that Tamalin plays a key role in the association of group 1 mGluRs with the ARF-specific GEF proteins and contributes to intracellular trafficking and the macromolecular organization of group 1 mGluRs at synapses. |
| Uniprot ID | Q9JJA9 |
| 基因名全称 | General receptor for phosphoinositides 1-associated scaffold protein |
| 推荐稀释比 | ELISA:1:4,000 - 1:20,000 IP:1μg WB:1:500 - 1:3,000 |
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